Table 1.
Baseline characteristics of participants by GSTM1 copy number (n=5715)
| Characteristic | White | Black | ||||||
|---|---|---|---|---|---|---|---|---|
| 0 Copy | 1 Copy | 2 Copies | P Value | 0 Copy | 1 Copy | 2 Copies | P Value | |
| N | 1772 | 1379 | 310 | 576 | 1093 | 585 | ||
| Age, yr, mean (SD) | 54.7 (5.7) | 54.4 (5.6) | 55.0 (5.6) | 0.19 | 54.0 (5.9) | 53.4 (5.8) | 53.8 (5.7) | 0.12 |
| Men, n (%) | 821 (46.3) | 639 (46.3) | 151 (48.7) | 0.73 | 211 (36.6) | 406 (37.1) | 207 (35.4) | 0.77 |
| BMI, mean (SD) | 27.1 (4.7) | 27.0 (4.8) | 27.0 (4.6) | 0.97 | 29.6 (5.8) | 29.6 (6.3) | 29.9 (6.6) | 0.57 |
| Smoking, n (%) | 0.92 | 0.36 | ||||||
| Current smoker | 445 (25.1) | 328 (23.8) | 73 (23.5) | 178 (30.9) | 321 (29.4) | 159 (27.2) | ||
| Former smoker | 652 (36.8) | 521 (37.8) | 116 (37.4) | 151 (26.2) | 258 (23.6) | 146 (25.0) | ||
| Never smoked | 675 (38.1) | 530 (38.4) | 121 (39) | 247 (42.9) | 514 (47) | 280 (47.9) | ||
| Diabetes, n (%) | 153 (8.6) | 106 (7.7) | 27 (8.7) | 0.60 | 107 (18.6) | 197 (18) | 98 (16.8) | 0.70 |
| Hypertension, n (%) | 511 (28.8) | 370 (26.8) | 92 (29.7) | 0.38 | 322 (55.9) | 563 (51.5) | 309 (52.8) | 0.23 |
| Coronary heart disease, n (%) | 70 (4.0) | 71 (5.1) | 18 (5.8) | 0.16 | 27 (4.7) | 44 (4) | 18 (3.1) | 0.36 |
| eGFR, ml/min per 1.73 m2, mean (SD) | 98.9 (13.0) | 99.5 (12.8) | 98.6 (13.9) | 0.41 | 111.0 (19.0) | 112.6 (18.9) | 111.5 (18.4) | 0.20 |