Figure 6.

Spikes are detected from ABLE-extracted time courses with high accuracy. On an in vitro dataset (21 imaging videos, each 30 s long), we demonstrate spike detection performance compared to electrophysiological ground truth on time courses extracted from cells segmented by ABLE. We plot the labeled cells (A) and corresponding boundaries detected by ABLE (B) on the mean image of one imaging video. The extracted cellular time courses and detected spikes are plotted in C. Spike detection was performed with an existing algorithm (Reynolds et al., 2016; Oñativia et al., 2013). On average over all videos, 78% of spikes are detected with a precision of 88% D.