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Detection of matrix metalloproteinase-2 (MMP-2) and MMP-9 protein expression in clinicopathological tissues via immunohistochemistry (IHC) MMP-2 and MMP-9 are expressed in the cytoplasm and appear as brown granules; a proportion of positive cells >25% in the visual field represented high expression, otherwise, the result was categorized as low expression (×400).
