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. 2017 Sep 8;14(5):5845–5852. doi: 10.3892/ol.2017.6914

Table I.

Characteristic of the ANN patients with poor and good prognosis.

Characteristic Total Poor prognosis % Good prognosis % P-value
All 195 65 130
Age at diagnosis, years
  <35 5   2 3.1   3 2.3
  35 to <49 94 31 47.7   63 48.5
  >50 96 32 33.3   64 49.2 >0.05
Mean ± SD 54.0±10.2 54.1±10.1 >0.05
Menopausal status
  Premenopausal 92 30 46.2   62 48.0
  Postmenopausal 103 35 53.8   68 52.0 >0.05
Tumor size
  T1a+T1b 6   2 3.1   4 3.1
  T1c 40 14 21.5   26 20.0
  T2 137 45 69.2   92 70.8
  T3 12   4 6.2   8 6.1 >0.05
Family history
  Yes 29   9 13.8   20 15.4
  No 166 56 86.2 110 84.6 >0.05
Peritumoural vascular invasion
  Absent 176 54 83.1 123 94.6
  Present 19 11 16.9   7 5.4 0.009
Tumor grade
  Low 26   5 7.7   21 16.2
  Intermediate 128 40 61.5   88 67.7
  High 41 20 30.8   21 16.2 0.031
Molecular subtype
  ‘Luminal A-like’ 59 11 16.9   48 36.9
  ‘Luminal B-like (HER2 negative)’ 41 13 20.0   28 21.5
  ‘Luminal B-like (HER2 positive)’ 21   8 12.3   13 10.0
  ‘HER2 positive’ 23 12 18.5   11 8.5
  ‘Triple negative’ 51 21 32.3   30 23.1 0.026
Chemotherapy
  Yes 152 52 80.0 100 76.9
  No 43 13 20.0   30 23.1 >0.05
Radiotherapy
  Yes 48 15 23.1   33 25.4
  No 147 50 76.9   97 74.6 >0.05
Endocrine therapy
  No. of ER positive subtype 121 32 49.2   89 68.5
  Yes 108 28 43.1   80 61.5
  No 13   4 6.1   9 7.0 >0.05

Statistical tests for categorical variables were performed using the χ2 test; mean age was tested using the Mann-Whitney test. ANN, axillary lymph node-negative; HER2, human epidermal growth factor receptor 2; ER, estrogen-receptor.