Figure 2.

Effects of ginkgolic acid on the migration and invasion of SW480 cells. (A) SW480 cells at 90% confluence were treated with 10 µM ginkgolic acid or vehicle for 12 h, and a scratch assay was performed. Images were captured at 0 and 36 h at ×40 magnification. *P<0.05. (B) SW480 cells were seeded into a Matrigel-coated invasion chamber subsequent to treatment with ginkgolic acid at various concentrations (0, 10 and 20 µmol/l), and a Matrigel-invasion assay was performed at 48 h. The number of invaded cells was quantified by counting the cells from 10 random fields at ×20 magnification. Data are presented as the mean ± standard deviation. *P<0.05 vs. control.