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. 2017 Sep 15;14(5):5890–5898. doi: 10.3892/ol.2017.6959

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Copyright: © Wang et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 2. — Representative immunohistochemical double-staining patterns of four CD44/CD24 phenotypes in triple-negative breast cancer tissues. CD44 (brown) exhibited homogenous membranous distribution, and CD24 (red) showed membranous and cytoplasmic immunoreactivity. (A) A tumor representing the CD44⁻/CD24⁻ phenotype. (B) The predominant cells are CD44⁺/CD24⁻ cells, only a few cells are CD44⁺/CD24⁺ (black arrow). (C) A tumor tissue considered as representing the CD44⁺/CD24⁺ phenotype. (D) Almost all cells in this tumor are CD44⁻/CD24⁺ cells. Magnification, ×400. CD, cluster of differentiation.