Table I.
CTR1 expression, n | ||||
---|---|---|---|---|
Characteristics | Patients, n | Low | High | P-value |
All patients | 293 | 177 | 116 | |
Age, years | 0.077a | |||
≤55 | 145 | 95 | 50 | |
>55 | 148 | 82 | 66 | |
Sex | 0.870a | |||
Female | 90 | 55 | 35 | |
Male | 203 | 122 | 81 | |
Tumor size, cm | 0.576a | |||
≤4 | 165 | 102 | 63 | |
>4 | 128 | 75 | 53 | |
T classification | <0.001b | |||
T1 | 185 | 132 | 53 | |
T2 | 27 | 13 | 14 | |
T3 | 77 | 31 | 46 | |
T4 | 4 | 1 | 3 | |
N classification | 0.489a | |||
N0 | 35 | 17 | 18 | |
N1 | 2 | 0 | 2 | |
Nx | 256 | |||
Distant metastasis | 0.726a | |||
No | 277 | 168 | 109 | |
Yes | 16 | 9 | 7 | |
Tumor, node, metastasis stage | <0.001b | |||
I | 179 | 128 | 51 | |
II | 23 | 10 | 13 | |
III | 71 | 29 | 42 | |
IV | 20 | 10 | 10 | |
Fuhrman grade | 0.003b | |||
1 | 31 | 20 | 11 | |
2 | 217 | 140 | 77 | |
3 | 42 | 17 | 25 | |
4 | 3 | 0 | 3 | |
Necrosis | 0.194a | |||
Absent | 252 | 156 | 96 | |
Present | 41 | 21 | 20 | |
Eastern Cooperative Oncology Group performance status | 0.018b | |||
0 | 214 | 137 | 77 | |
1 | 64 | 33 | 31 | |
2 | 11 | 7 | 4 | |
3 | 4 | 0 | 4 |
χ2 test or Fisher's exact test.
Cochran-Mantel-Haenszel χ2 test. P<0.05 was considered to indicate a statistically significant difference. CTR1, copper transporter 1.