Table IV.
Comparison of the predictive accuracy of the prognostic models.
| Overall survival (n=293) | Disease free survival (n=268) | |||||
|---|---|---|---|---|---|---|
| Models | C-index | P-valuea | AIC | C-index | P-valuea | AIC |
| CTR1 | 0.654 | 878.03 | 0.664 | 736.39 | ||
| TNM | 0.702 | 865.51 | 0.653 | 746.76 | ||
| TNM + CTR1 | 0.750 | 0.003 | 849.72 | 0.722 | 0.015 | 726.30 |
| SSIGN | 0.740 | 858.94 | 0.725 | 722.78 | ||
| SSIGN + CTR1 | 0.779 | 0.024 | 839.81 | 0.763 | 0.090 | 705.21 |
| UISS | 0.722 | 861.26 | 0.713 | 726.29 | ||
| UISS + CTR1 | 0.766 | 0.021 | 842.16 | 0.750 | 0.021 | 711.79 |
a
C-index compared with the original model without CTR1 expression. C-index, concordance index; AIC, Akaike information criterion; SSIGN, Mayo clinic stage, size, grade and necrosis score; UISS, University of California Integrated Staging System; TNM, tumor-node-metastasis; CTR1, copper transporter 1.