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. 2017 Oct 24;10:5151–5163. doi: 10.2147/OTT.S148681

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© 2017 Zhou et al. This work is published and licensed by Dove Medical Press Limited

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MPC1 expression was closely correlated with TNM stage in patients with GC.

Notes: (A) Representative images of MPC1 staining in normal gastric mucosa and GC samples at different infiltration depths. Scale bar, 50 μm; magnification ×200. (B) IHC scores of MPC1 in patients with TNM III/IV tumors were significantly lower compared with TNM I/II tumors (P=0.005). (C) Analysis of NCBI GEO dataset GSE26942 showed that the mRNA levels of MPC1 in TNM III/IV cases were obviously lower than those of TNM I/II cases (P=0.016).

Abbreviations: TNM, tumor node metastasis; GC, gastric cancer; IHC, immunohistochemistry.