Figure 4.
Overexpression of MPC1 attenuated the proliferative, migrating, and invasive abilities of human GC cells.
Notes: (A) The overexpression of MPC1 in MPC1-FLAG and control GC cells (SGC7901 and MGC803) was tested by Western blotting analysis. (B) Representative images of colonies formed in control and MPC1-FLAG GC cells. (C) Histograms showing the number of colonies. The means ± standard deviations from three independent experiments were shown. (D) The growth rate of control and MPC1-FLAG GC cells (SGC7901 and MGC803) was determined by cell counting kit-8 (CCK-8) assay. (E, F) Transwell chamber migration and Matrigel-invasion assays for MPC1-FLAG and control GC cells (SGC7901 and MGC803). **P<0.01, ***P<0.001. Scale bar, 50 μm; magnification ×200.
Abbreviation: GC, gastric cancer.