Table II.

Univariate and multivariate Cox regression analysis of CDX2 expression and other parameters for cancer-specific survival.

A, Univariate analysis
Variable	HR (95% CI)	P-value
CDX2 expression
Negative vs. positive	2.60 (1.37–5.27)	0.003
Age, years
>65 vs. ≤65	1.48 (0.81–2.75)	0.206
Gender
Male vs. female	0.95 (0.51–1.89)	0.888
Histological type
Undifferentiated vs. differentiated	1.07 (0.59–1.96)	0.814
Stage
III vs. I & II	6.50 (3.52–12.50)	<0.001
B, Multivariate analysis
Variable	HR (95% CI)	P-value
CDX2 expression
Negative vs. positive	2.10 (1.05–4.41)	0.035
Age, years
>65 vs. ≤65	2.11 (1.14–4.00)	0.018
Gender
Male vs. female	0.99 (0.50–2.02)	0.967
Histological type
Undifferentiated vs. differentiated	0.69 (0.36–1.32)	0.266
Stage
III vs. I and II	7.10 (3.72–14.08)	<0.001

CDX2, caudal-type homeobox protein 2; HR, hazard ratio; CI, confidence interval.