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. 2017 Oct 24;12:7777–7787. doi: 10.2147/IJN.S144634

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© 2017 Lian et al. This work is published and licensed by Dove Medical Press Limited

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Preparation and characterization of HSA–ICG–DTX complex. (A) TEM images of HAS@DTX, HSA@IR780, and HSA@IR780@DTX. (B) Hydrodynamic diameters of HAS@DTX, HSA@IR780, and HSA@IR780@DTX measured by DLS. (C) UV–Vis–NIR spectra of Free IR780, HAS@DTX, HSA@IR780, and HSA@IR780@DTX. (D) Temperature change of PBS, HSA@IR780, and HSA@IR780@DTX in the irradiation of a NIR laser (808 nm) with a power density of 1 W/cm². (E) Singlet oxygen generation of NPs after NIR laser irradiation. (F) Release profiles of HSA@IR780@DTX with or without laser irradiation.

Abbreviations: DTX, docetaxel; FL, fluorescence; HSA, human serum albumin; NIR, near-infrared; PBS, phosphate buffer saline; SOSG, singlet oxygen sensor green; ICG, indocyanine green.

Preparation and characterization of HSA–ICG–DTX complex. (A) TEM images of HAS@DTX, HSA@IR780, and HSA@IR780@DTX. (B) Hydrodynamic diameters of HAS@DTX, HSA@IR780, and HSA@IR780@DTX measured by DLS. (C) UV–Vis–NIR spectra of Free IR780, HAS@DTX, HSA@IR780, and HSA@IR780@DTX. (D) Temperature change of PBS, HSA@IR780, and HSA@IR780@DTX in the irradiation of a NIR laser (808 nm) with a power density of 1 W/cm². (E) Singlet oxygen generation of NPs after NIR laser irradiation. (F) Release profiles of HSA@IR780@DTX with or without laser irradiation.

Abbreviations: DTX, docetaxel; FL, fluorescence; HSA, human serum albumin; NIR, near-infrared; PBS, phosphate buffer saline; SOSG, singlet oxygen sensor green; ICG, indocyanine green.