Figure 2.

Confocal fluorescence images of ROS generation in MCF-7 cells. From top to bottom: HSA@IR780 NPs, HSA@IR780 NPs plus NIR laser (808 nm, 1 W/cm², 2 min), HSA@IR780@DTX NPs and HSA@IR780@DTX NPs plus NIR laser. The final concentration of HSA@IR780 NPs (calculated as IR780) was 5 µg/mL. The green fluorescence color represents oxidatively stressed cells affected with ROS. Fluorescence images were collected at 510~560 nm, under an excitation at 504 nm. The scale bar is 20 µm.

Abbreviations: DTX, docetaxel; HSA, human serum albumin; NIR, near-infrared; NPs, nanoparticles.