Table 1. Functional miRNAs involved in BCSC biology.

Stem cell biology	Functions	miRNAs involved
Self-renewal	Anti-BCSC	Let-7 family (let-7a, let-7b, let-7c, let-7d, let-7e, let-7f, let-7g, let-7i, miR-98), miR-200 family (miR-200a, miR-200b, miR-200c, miR-141, miR-429), miR-30 family(miR30a, miR-30b, miR-30c, miR-30d, miR-30e), miR-34c, miR34a, miR-128, miR-27b, miR-100, miR-205
	Pro-BCSC	MiR-495
Proliferation and differentiation	Anti-BCSC	Let-7 family, miR-200 family, miR-30 family, miR-34c, miR-93, miR-128, miR-16, miR-140, miR-27a, miR-205
	Pro-BCSC	MiR-93, miR-495, miR-181 family (miR-181a, miR-181b, miR-181c), miR-29, miR-142, miR-221, miR-135b
Tumorigenicity	Anti-BCSC	Let-7 family, miR-200c, miR-205
	Pro-BCSC	MiR-142
EMT	Anti-BCSC	Let-7 family, miR-200 family, miR-30 family, miR-34c, miR-7, miR-128, miR-93, miR-205
	Pro-BCSC	MiR-181, miR-21, miR-495, miR-22, miR-221, miR-9
Invasion and metastasis	Anti-BCSC	Let-7 family, miR-200a, miR-34c, miR-93, miR-7
	Pro-BCSC	MiR-22, miR-21, miR-9
Chemoresistance	Anti-BCSC	MiR-128, miR-16, miR34a
	Pro-BCSC	MiR-125b

Abbreviations: BCSC, breast cancer stem cell; EMT, epithelial to mesenchymal transition; miR, microRNA.