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. 2017 Jul 28;2:17029. doi: 10.1038/sigtrans.2017.29

Table 1. Human ZnT proteins.

Protein Major location of protein expression Subcellular localization
ZnT1 Ubiquitous Plasma membrane22
ZnT2 Mammary gland, pancreas, prostate, retina, intestine, kidney23,24,25,26,27 Endosome, lysosome, secretory vesicle, plasma membrane23,24
ZnT3 Brain, pancreas, testis28,29 Synaptic vesicles30
ZnT4 Mammary gland, placenta, prostate, kidney, brain25,26,31,32,33,34 Endosome, secretory vesicle, plasma membrane26,31
ZnT5 Heart, placenta, prostate, ovary, testis, intestine, thymus, bone25,32,35 Golgi, vesicles, plasma membrane36
ZnT6 Brain, lung, intestine34,37 Golgi, vesicles37
ZnT7 Intestine, stomach, pancreas, prostate, placenta, testis, retina, muscle25,32,38 Golgi, vesicles38
ZnT8 Pancreas, adrenal gland, thyroid, testis39,40 Secretory granule39
ZnT9 Brain, muscle, kidney41 ER41
ZnT10 Brain, retina, liver42 Golgi, plasma membrane42