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. 2017 Jul 28;2:17029. doi: 10.1038/sigtrans.2017.29

Table 2. Human ZIP proteins.

Protein Sub-family Major location of protein expression Subcellular localization
ZIP1 ZIPII Prostate, small intestine, kidney, liver, pancreatic α cells29,44,45,46 Plasma membrane, ER46,47
ZIP2 ZIPII Prostate, uterine, epithelial cells, ovary liver, skin48,49 Plasma membrane50,51
ZIP3 ZIPII Testes, pancreatic cells52 Plasma membrane53
ZIP4 LIV-1 Small intestine, stomach, colon, cecum, kidney, pancreatic β cells29,54 Plasma membrane55
ZIP5 LIV-1 Liver, kidney, spleen colon, pancreas56 Plasma membrane56
ZIP6 LIV-1 Testis, pancreatic β cells57,58 Plasma membrane57
ZIP7 LIV-1 Brain, liver, pancreatic β cells58,59 Golgi, ER60
ZIP8 LIV-1 Pancreas, placenta, lung, liver, testis, thymus, red blood cells57,61,62 Plasma membrane, lysosome, endosomes61
ZIP9 ZIPI Prostate63 Golgi64
ZIP10 LIV-1 Testis, kidney, breast, pancreatic α cells, red blood cells29,57,62,65,66 Plasma membrane57,67
ZIP11 gufA Mammary gland, testis, stomach, ileum and cecum68,69 Golgi68
ZIP12 LIV-1 Neurons, endothelial, smooth muscle and interstitial cells70,71 Unknown
ZIP13 LIV-1 Retinal pigment epithelial cell line, osteoblasts27,72 ER73
ZIP14 LIV-1 Liver, heart, placenta, lung, brain, pancreatic α cells29,74 Plasma membrane, mitochondria, endosome, lysosome75,76