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. 2017 Oct 9;2:17054. doi: 10.1038/sigtrans.2017.54

Figure 2.

Figure 2

The change of the spleen size and CD20+ B-cell counts in the PB of patients UPNII-09. (a) The whole-body 2-[18F]-fluoro-2-deoxy-D-glucose positron emission tomography (FDG-PET) scans show the larger spleen over the midline of body at 4 months after infusion, then shrink to midline and left midline, respectively, at 12 and 24 months. Especially at 36 months after infusion, the size of spleen become almost normal. (b) The CD20+ lymphocyte cells determined by flow cytometry in PB after CART-20 cell infusion is shown. From 1 week after infusion, the proportion began to decline, and it lasted for over 150 weeks.