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. 2017 Oct 25;12:7833–7846. doi: 10.2147/IJN.S140661

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© 2017 Tokajuk et al. This work is published and licensed by Dove Medical Press Limited

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Magnetic nanoparticles increase anti-biofilm activity of chlorhexidine in the presence of human saliva.

Notes: Preventive activity of free CHX and MNP@CHX against biofilm-forming pathogens in the presence of human saliva (A–D). Effective inhibition of mixed-species biofilm formation in the presence of human saliva (E–G). *Statistically significant (P≤0.05) activity of magnetic nanoparticles coated by chlorhexidine compared to nonimmobilized drugs.

Abbreviations: CHX, chlorhexidine; MNP@CHX, magnetic nanoparticles functionalized by chlorhexidine; MRSA, methicillin-resistant Staphylococcus aureus.

Magnetic nanoparticles increase anti-biofilm activity of chlorhexidine in the presence of human saliva.

Notes: Preventive activity of free CHX and MNP@CHX against biofilm-forming pathogens in the presence of human saliva (A–D). Effective inhibition of mixed-species biofilm formation in the presence of human saliva (E–G). *Statistically significant (P≤0.05) activity of magnetic nanoparticles coated by chlorhexidine compared to nonimmobilized drugs.

Abbreviations: CHX, chlorhexidine; MNP@CHX, magnetic nanoparticles functionalized by chlorhexidine; MRSA, methicillin-resistant Staphylococcus aureus.