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. 2017 Oct 25;12:7833–7846. doi: 10.2147/IJN.S140661

Figure 7.

Figure 7

Effect of chlorhexidine in free and immobilized forms on human osteoblast cell integrity, interleukin release and their growth.

Notes: Panels (A, B) show the release of LDH and IL-8 from human osteoblast after 24 h of treatment. The growth curves of untreated osteoblast cells (C) and after addition of magnetic nanoparticles (D), chlorhexidine (E) and MNP@CHX (F) from 5 to 250 μg/mL. *Statistically significant (P<0.05) compared to CHX in immobilized form.

Abbreviations: CHX, chlorhexidine; CT, untreated control; MNP@CHX, magnetic nanoparticles functionalized by chlorhexidine.