Table 3.
Factors associated with high WBC count in SCD patients, N=275 (116 high and 159 normal)
| Factor | B | SE | P-value | aOR | 95% CI for OR
|
|
|---|---|---|---|---|---|---|
| Lower | Upper | |||||
| Male | 1.289 | 0.363 | 0.001* | 3.63 | 1.783 | 7.384 |
| Age 25–36 years | −0.418 | 0.389 | 0.283 | 0.66 | 0.307 | 1.412 |
| Age >36 years | −0.249 | 0.435 | 0.567 | 0.78 | 0.332 | 1.829 |
| Fever | 0.159 | 0.339 | 0.638 | 1.17 | 0.604 | 2.277 |
| Cough | 0.779 | 0.356 | 0.029* | 2.18 | 1.084 | 4.378 |
| Shortness of breath | 0.025 | 0.395 | 0.949 | 1.03 | 0.473 | 2.222 |
| Wheezing | −0.816 | 0.423 | 0.054 | 0.44 | 0.193 | 1.013 |
| Tiredness | 0.220 | 0.396 | 0.579 | 1.25 | 0.573 | 2.708 |
| Swelling in hands/feet | 0.641 | 0.398 | 0.107 | 1.90 | 0.870 | 4.138 |
| Redness | −0.298 | 0.503 | 0.554 | 0.74 | 0.277 | 1.989 |
| Itching | 0.324 | 0.366 | 0.375 | 1.38 | 0.676 | 2.832 |
| Blood transfusion | −0.426 | 0.386 | 0.270 | 0.65 | 0.307 | 1.392 |
| Back pain | 0.662 | 0.361 | 0.066 | 1.94 | 0.956 | 3.930 |
| Leg pain | −0.934 | 0.383 | 0.015* | 0.39 | 0.185 | 0.833 |
| Arm pain | −0.057 | 0.336 | 0.865 | 0.94 | 0.489 | 1.825 |
| Chest pain | −0.110 | 0.348 | 0.751 | 0.90 | 0.453 | 1.770 |
| Frequent ED visits | 0.185 | 0.408 | 0.651 | 1.20 | 0.541 | 2.674 |
| Hemoglobin | −0.274 | 0.124 | 0.027* | 0.76 | 0.596 | 0.969 |
| Heart rate | −0.034 | 0.016 | 0.032* | 0.97 | 0.936 | 0.997 |
| Hemoglobin F | 0.009 | 0.037 | 0.814 | 1.01 | 0.938 | 1.084 |
| Hemoglobin A2 | −0.022 | 0.128 | 0.863 | 0.98 | 0.762 | 1.256 |
| Hemoglobin S | 0.034 | 0.031 | 0.273 | 1.03 | 0.973 | 1.100 |
Note:
*
Significant at α=0.05.
Abbreviations: aOR, adjusted odds ratio; CI, confidence interval; WBC, white blood cell; SCD, sickle cell disease; ED, emergency department.