Table 1.

Clinicopathological correlation of circRNA0003906 expression in CRC

Variables	Tumor circRNA0003906 expression		P-valuea
	Low	High
Age			0.419
<60 years	19	15
≥60 years	42	46
Gender			0.308
Male	47	42
Female	14	19
Tumor diameter			0.560
<5 cm	40	43
≥5 cm	21	18
Differentiation			0.026
Well + moderate	31	43
Poor	30	18
T classification			0.147
1–2	25	33
3–4	36	28
N classification			<0.001
0	21	46
1–2	40	15
TNM stage			0.146
I–II	29	37
III–IV	32	24
CEA			0.389
Negative	45	49
Positive	16	12
CA199			0.783
Negative	54	53
Positive	7	8

Notes: CRC patients receiving radical operation were segregated into circRNA0003906 high/low expression groups (calculation of cut-off by ROC analysis).

^aStatistical analyses were performed with χ² test or Fisher’s exact test.

Abbreviations: CA199, carbohydrate antigen 19-9; CEA, carcinoembryonic antigen; CRC, colorectal cancer; ROC, receiver operating characteristics.