Skip to main content
. Author manuscript; available in PMC: 2018 Sep 21.
Published in final edited form as: Nanoscale. 2017 Sep 21;9(36):13465–13476. doi: 10.1039/c7nr02363d

Figure 2. In situ Stability of the PZn3-loaded PEG-b-TCL-based micelles.

Figure 2

(A) Cryo-TEM image, (B) absorbance spectrum that is corrected for light scattering, and (inset) fluorescence emission spectrum of PZn3-loaded PEG-b-TCL-based micelles in aqueous suspension (λex = 492 nm). (C) Changes in the hydrodynamic size over 30 days in different environments (pH = 7.4 vs. pH = 5.50. (D) Variation of the emission intensities of PZn3 in aqueous suspensions of PEG-b-TCL-based micelles that were placed in plasma at 37 °C and as a function of time. Integration of the emissive signal from PZn3 over time (right) was obtained by calculating the area under the curve (AUC) and was used to determine its fluorescence emission half-life within micelles suspensions upon transfer to plasma. ε: extinction coefficient.