Table 3.
Results of Regression Analysis of the Relationship between Void Size and Inter-Void Interval and between Void Size and EMG Properties
Thoraco-lumbar | Mid-thoracic | |||||||
---|---|---|---|---|---|---|---|---|
Intact | Transected | Intact | Transected | |||||
Independent Variable (z-scores) | Slope | r2 | Slope | r2 | Slope | r2 | Slope | r2 |
Inter-void interval | 0.49 | 0.29*** | 0.16¶¶¶ | 0.03*** | 0.56 | 0.29*** | 0.34¶¶¶ | 0.12*** |
Void duration | 0.54 | 0.30*** | 0.53 | 0.33*** | 0.92 | 0.49*** | 0.43¶¶¶ | 0.21*** |
Pburst | 0.29 | 0.05*** | 0.37 | 0.11*** | 0.35 | 0.04*** | 0.46¶¶ | 0.09*** |
P3–5 | 0.21 | 0.05*** | 0.24 | 0.07*** | 0.32 | 0.10*** | 0.17¶¶ | 0.03*** |
P8–12 | −0.07 | 0.00 | 0.05 | 0.00 | 0.02 | 0.00 | 0.06 | 0.00 |
Bursting time | 0.41 | 0.13*** | 0.53 | 0.30*** | 0.63 | 0.25*** | 0.52¶ | 0.19*** |
Silent period | 0.52 | 0.19*** | −0.04¶¶¶ | 0.00 | 0.39 | 0.16** | −0.13¶¶ | 0.02 |
Active period | 0.31 | 0.13** | −0.05¶ | 0.00 | 0.19 | 0.03 | 0.07 | 0.01 |
Bursting period | 0.51 | 0.22*** | −0.06¶¶¶ | 0.00 | 0.40 | 0.17** | −0.06¶¶ | 0.00 |
Slope and r2, slope and coefficient of determination for regression of void size on independent variable; void duration, time of urine weight increase; Pburst, power in bursting range of as a percent of total power; P3–5, power at 3–5 Hz (i.e., low bursting frequencies) as a percent of total power; P8–12, power at 8–12 Hz (i.e., high bursting frequencies) as a percent of total power; bursting time, cumulative time during void when power in bursting frequencies exceeds the power in the same range expressed as a percent of total power of amplitude-matched non-voiding epochs by 2 standard deviations; silent period, time during a single bursting cycle in which the external urethral sphincter electromyography (EUS EMG) was not active; active period, time during a single bursting cycle in which the EUS EMG was active; bursting period, duration of a single bursting cycle (i.e., active period + silent period). All variables were z-transformed prior to regression analysis to remove inter-animal differences in mean and variance. For r2, asterisks denote significant relationships between the independent variable and void size. For slope, ¶ denotes significant difference in slope, compared with intact. * or ¶, p ≤ 0.05; ** or ¶¶, p < 0.01,*** or ¶¶¶, p < 0.001.