Table 2. Association Between Orthostatic Hypotension and Self-reported Dizziness on Standing According to Measurementa.
BP Assessment | Measure | Dizziness, OR (95% CI) [n = 1138] |
P Value |
---|---|---|---|
Orthostatic hypotension | 1 | 1.49 (1.18-1.89) | .001 |
2 | 1.04 (0.83-1.30) | .72 | |
3 | 1.11 (0.87-1.42) | .38 | |
4 | 1.11 (0.85-1.44) | .45 | |
5 | 0.77 (0.49-1.22) | .27 | |
Postural change in SBP, per −5 mm Hg | 1 | 1.03 (1.00-1.05) | .06 |
2 | 1.02 (0.99-1.04) | .21 | |
3 | 0.99 (0.97-1.02) | .70 | |
4 | 0.99 (0.96-1.02) | .52 | |
5 | 0.97 (0.93-1.00) | .07 | |
Postural change in DBP, per −5 mm Hg | 1 | 1.05 (1.00-1.10) | .05 |
2 | 0.96 (0.91-1.01) | .13 | |
3 | 0.98 (0.93-1.04) | .52 | |
4 | 0.98 (0.93-1.03) | .41 | |
5 | 0.92 (0.86-0.99) | .02 |
Abbreviations: BP, blood pressure; DPB, diastolic blood pressure; OR, odds ratio; SBP, systolic blood pressure.
All models adjusted for age, sex, race-study center, heart rate, body mass index, estimated glomerular filtration rate, diabetes, hypertension, alcohol use, education level, smoking status, leisure index, prior coronary heart disease, prior stroke, prior congestive heart failure, hypertension medication use in past 2 weeks, diuretic use, antidepressant use, sedative use, hypnotic use, antipsychotic medication use, anticholinergic medication use, resting SBP, and resting DBP. Unlike eTable 5 in the Supplement, each model includes only 1 measurement of orthostatic hypotension or postural change in SBP or DBP at a time. Measurement 5 has a much smaller sample size. There were 11 429 participants with 1138 reporting dizziness for measurements 1 to 4. There were 7385 participants with 670 reporting dizziness for measurement 5.