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Basics of endosomal sorting. All internalized cargo gets sorted into the early endosome. From the early endosome, cargo sorts into distinct compartments which then bud off to form recycling endosomes (Rab4, Rab11), or late endosomes (Rab7) which mature into lysosomes, or sort back to the TGN through retromer. [Color figure can be viewed at wileyonlinelibrary.com]
