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. Author manuscript; available in PMC: 2018 Jan 15.
Published in final edited form as: Clin Cancer Res. 2017 Feb 3;23(14):3794–3801. doi: 10.1158/1078-0432.CCR-16-2196

Table 1.

Baseline characteristics by treatment arm

Bevacizumab
(N=189)
Standard
(N=170)
Total
(N=359)
Molecular subgroup
  Differentiated 36 (19.0%) 37 (21.8%) 73 (20.3%)
  Immunoreactive 69 (36.5%) 53 (31.2%) 122 (34.0%)
  Mesenchymal 37 (19.6%) 31 (18.2%) 68 (18.9%)
  Proliferative 47 (24.9%) 49 (28.8%) 96 (26.7%)
Age (years) at randomization
  Mean (SD) 58.1 (11.0) 57.4 (11.2) 57.8 (11.1)
  Range (26.0–80.0) (21.0–80.0) (21.0–80.0)
Race
  White 189 (100.0%) 167 (98.2%) 356 (99.2%)
  Asian 0 (0.0%) 3 (1.8%) 3 (0.8%)
ECOG score
  0 77 (40.7%) 78 (45.9%) 155 (43.2%)
  1 93 (49.2%) 83 (48.8%) 176 (49.0%)
  2 19 (10.1%) 9 (5.3%) 28 (7.8%)
Origin of cancer
  Ovary 169 (89.4%) 150 (88.2%) 319 (88.9%)
  Fallopian tube 7 (3.7%) 7 (4.1%) 14 (3.9%)
  Primary peritoneum 12 (6.3%) 12 (7.1%) 24 (6.7%)
  Multiple sites 1 (0.5%) 1 (0.6%) 2 (0.6%)
Histology
  Serous 150 (79.4%) 127 (74.7%) 277 (77.2%)
  Clear cell 7 (3.7%) 7 (4.1%) 14 (3.9%)
  Endometrioid 4 (2.1%) 6 (3.5%) 10 (2.8%)
  Mucinous 3 (1.6%) 2 (1.2%) 5 (1.4%)
  Mixed 15 (7.9%) 21 (12.4%) 36 (10.0%)
  Other 10 (5.3%) 7 (4.1%) 17 (4.7%)
FIGO stage
  I/IIA 14 (7.4%) 12 (7.1%) 26 (7.2%)
  IIB/IIC 12 (6.3%) 11 (6.5%) 23 (6.4%)
  III 134 (70.9%) 117 (68.8%) 251 (69.9%)
  IV 29 (15.3%) 30 (17.6%) 59 (16.4%)
Outcome of surgery
  Optimal 145 (76.7%) 129 (75.9%) 274 (76.3%)
  Sub-Optimal 43 (22.8%) 40 (23.5%) 83 (23.1%)
  missing 1 (0.5%) 1 (0.6%) 2 (0.6%)
High-risk of progression*
  No 130 (68.8%) 110 (64.7%) 240 (66.9%)
  Yes 59 (31.2%) 60 (35.3%) 119 (33.1%)
Grade
  1 or 2 46 (24.5%) 28 (16.8%) 74 (20.8%)
  3 142 (75.5%) 139 (83.2%) 281 (79.2%)
  Missing 1 3 4
*

High risk of progression: suboptimal debulked stage III, inoperable Stage III, all stage IV patients.