Table 3.
Association between SNP rs4939827 and the Mediterranean dietary pattern adherence in relation with colorectal cancer taking into account the genotype
| Cases | Controls | Adjusted OR | ||||
|---|---|---|---|---|---|---|
| n | % | n | % | OR | CI 95% | |
| Low | 341 | 31.4 | 594 | 24.7 | 1 | – |
| TT | 110 | 32.2 | 171 | 28.8 | 1 | – |
| CT | 169 | 49.6 | 302 | 50.8 | 0.83 | 0.59–1.17 |
| CC | 62 | 18.2 | 121 | 20.4 | 0.70 | 0.44–1.08 |
| Medium | 431 | 39.7 | 1010 | 41.9 | 0.85 | 0.70–1.03 |
| TT | 154 | 35.7 | 316 | 31.29 | 1 | – |
| CT | 211 | 49 | 478 | 47.2 | 0.87 | 0.65–1.15 |
| CC | 66 | 15.3 | 216 | 21.38 | 0.64 | 0.44–0.93 |
| High | 315 | 29.0 | 805 | 33.4 | 0.64 | 0.51–0.79 |
| TT | 123 | 39.1 | 242 | 30.1 | 1 | – |
| CT | 144 | 45.7 | 405 | 50.3 | 0.75 | 0.55–1.02 |
| CC | 48 | 15.2 | 158 | 19.6 | 0.63 | 0.42–0.96 |
CT vs TT: Adjusted Odd Ratio (OR) = 0.82 and 95% Confidence Interval (CI) = 0.69–0.98
CC vs TT: OR = 0.65 and 95% CI = 0.51–0.81
The adjusted odds ratios (OR) was calculating taking into account the variables sex, age, educational level, BMI, total energy intake, family history fist degree, METS. Area was used as random variable (N: Number; CI: Confidence Interval)