Fig. 10.

Gene expression analysis of genes involved in the epidermal growth factor (EGF) signaling pathway in glioblastoma cells (U87MG cell line) after 24 h of treatment. Ctrl: Control samples cultured cells with 3% fetal bovine serum, PDT: (photodynamic therapy) samples NE/ClAlPc subjected to sunlight at a dose of 100 mJ/cm². Genes: AKT1, AKT2, AKT3: RAC–alpha serine/threonine-protein kinase, EFGR: epidermal growth factor receptor, MAP2K1: mitogen-activated protein kinase kinase 1, MAP2K4: mitogen-activated protein kinase kinase 4, MAP3K1: mitogen-activated protein kinase kinase kinase 1, MAPK1: mitogen-activated protein kinase 1, MAPK3: mitogen-activated protein kinase 3, MAPK8: mitogen-activated protein kinase 8, MAPK9: mitogen-activated protein kinase 9, NFKB1: nuclear factor NF-kappa-B p105 subunit, PIK3C2B: phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing beta polypeptide, PIK3CA: phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha, PIK3CB: phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta isoform, PIK3CD: phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta isoform, PIK3R1: phosphatidylinositol 3-kinase regulatory subunit alpha. Statistical significance was set at *p < 0.05