Fig. 2.

Tracking conformational changes on a protein with SRCD spectroscopy. Comparison of conventional CD (a) and SRCD (b) spectra of MEG-14 in 10 mM sodium phosphate buffer, pH 7.4 (black), and in the presence 25% (gray), 50% (light gray), and 75% (red) trifluoroethanol (TFE). Adapted from Kumagai et al. (2017) with permission