Table 2B.

SUVr PiB comparisons of the patient with PT21 based on the Crawford-Howell t-test and one-tailed p-values for the site #2 data. T-value and associated p-values are tabulated for each sample and brain region, separately. P-values, shown in parentheses, were adjusted for multiple comparisons using Holm’s method [44]. AD: Alzheimer’s disease. TDS: Typical Down syndrome.

Region	t-TDS	p-TDS (adj)	t-AD	p-AD (adj)
Frontal	−1.96	0.07 (0.92)	−1.69	0.12 (1.0)
Parietal	−1.48	0.12 (1.0)	−1.44	0.15 (1.0)
Temporal	−1.39	0.13 (1.0)	−1.64	0.12 (1.0)