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. Author manuscript; available in PMC: 2018 Aug 4.
Published in final edited form as: J Mol Biol. 2017 Jul 3;429(16):2427–2437. doi: 10.1016/j.jmb.2017.06.019

Figure 1.

Figure 1

Co-transcriptional RNA processing could be misregulated with age. Processes that have been shown to be up or downregulated with age are indicated by the red and blue arrows respectively. Processes that could be misregulated with age, but have not yet been examined in sufficient detail are indicated by grey question marks. CTD, carboxy-terminal domain of RNA polymerase II, PIC, pre-initiation complex; CTD; RNA pol II, RNA polymerase II.