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. Author manuscript; available in PMC: 2018 Aug 4.
Published in final edited form as: J Mol Biol. 2017 Jul 3;429(16):2427–2437. doi: 10.1016/j.jmb.2017.06.019

Figure 2.

Figure 2

An overview of age-associated transcriptome changes. Only 2 – 3 % of the whole genome (upper panel) shows age-associated changes in transcript levels. These changes between young and old cells are depicted in the two lower panels. Transcripts are shown with exons depicted as boxes, and introns and untranslated regions as lines. Transcripts that increase or decrease with age are shown in red and blue respectively, versus unchanged transcripts in black. Potential splice variants are shown in purple that include intron retention (third transcript from top) and exon skipping (bottom right).