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. Author manuscript; available in PMC: 2018 Oct 1.
Published in final edited form as: Top Magn Reson Imaging. 2017 Oct;26(5):201–209. doi: 10.1097/RMR.0000000000000137

Figure 4.

Figure 4

Therapeutic-induced changes in breast tumor ADC values. MRI images are depicted for non-responding (top row) and responding (bottom row) patients treated for breast cancer. (A) and (E) T1-weighted gadolinium enhanced, (B) and (F): pre-treatment ADC maps, (C) and (G): ADC maps at 8–11 days after treatment initiation, D) and (H): Histograms of ADC values in the tumor pre-treatment and post-treatment initiation. Tumor is delineated from surrounding healthy tissue in the individual images by the purple line. (Reprinted from Galban CJ, Ma B, Malyarenko D, et al. Multi-site clinical evaluation of DW-MRI as a treatment response metric for breast cancer patients undergoing neoadjuvant chemotherapy. PLoS One 2015;10(3):e0122151; with permission.)