Table 1. Dissociation constants (Kd) values of ligands for cT1R1-NTD.
Ligand |
Kd [μM] No IMP |
Kd [μM] 0.3 μM IMP |
---|---|---|
IMP | 0.83 ± 0.06 | - |
L-Ala | 3.2 ± 0.3 | 1.8 ± 0.1 |
L-Ile | 7.3 ± 0.7 | 4.9 ± 0.6 |
L-Arg | 48.1 ± 1.7 | 32.9 ± 4.1 |
L-His | 83.4 ± 10.7 | 20.9 ± 1.4 |
The Kd values are reported as the mean ± SEM.