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. Author manuscript; available in PMC: 2018 Oct 30.
Published in final edited form as: Chem Soc Rev. 2017 Oct 30;46(21):6532–6552. doi: 10.1039/c7cs00445a

Figure 5.

Figure 5

Thiol-ene photopolymerizations used to functionalize three-dimensional hydrogels. a) Norbornene-modified PEG can be crosslinked and functionalized with cysteine-containing peptides. hMSCs seeded in MMP-degradable hydrogels spread only in regions with photopatterned RGD. Reproduced from Fairbanks et al.71 copyright (2009) Wiley. b) Left: nanofibrous norbornene hyaluronic acid hydrogels patterned with three fluorescent peptides. Right: when RGD patterns are created perpendicular to the nanofiber alignment, cells localize to the RGD regions (indicated in red), but align with the fiber orientation. Scale bars 100 μm (left) and 200 μm (right). Reproduced from Wade et al.159 copyright (2015) Wiley.

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