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Partial amino acid sequence alignments of the SPRY1 and Handle domain of RyR1 orthologs and paralogs in teleost and mammalian species. Areas highlighted in red are suggested to be important for FKBP1 binding (Yan et al.2015 and Yuchi et al. 2015). Abbreviations D.R. Danio rerio, F.H Fundulus heteroclitus.
