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Amino acid sequence alignments of FK506 binding protein 1 orthologs and paralogs in teleost and mammalian species. Areas highlighted in black and red are suggested to be important for FKBP1’s interaction with the RyR SPRY1 or Handle domain, respectively (Yan et al. 2015 and Yuchi et al. 2015). Abbreviations D.R. Danio rerio, F.H Fundulus heteroclitus.
