Table 2.
Functional enrichment of differentially expressed genes (DEGs) in peripheral blood mononuclear cells 6 DPI.
| Gene Ontology | False discovery rate adjusted p-value | Number of DEGs |
|---|---|---|
| Upregulated | ||
| Immune system process | 3.02−82 | 358 |
| Defense response | 2.19−63 | 255 |
| Response to stress | 2.73−61 | 418 |
| Innate immune response | 7.57−47 | 154 |
| Response to cytokine | 1.34−45 | 173 |
| Inflammatory response | 1.61−34 | 117 |
| Cell death | 7.53−32 | 158 |
| Signal transduction | 9.15−29 | 436 |
| Positive regulation of metabolic process | 1.07−28 | 312 |
| Myeloid leukocyte activation | 3.05−23 | 47 |
| Downregulated | ||
| Regulation of signal transduction | 6.16−10 | 103 |
| Leukocyte activation | 8.85−10 | 40 |
| Immune system process | 1.51−9 | 90 |
| Lymphocyte activation | 1.08−8 | 34 |
| Regulation of cell motility | 6.82−11 | 44 |
| Positive regulation of metabolic process | 1.06−7 | 104 |
| Adaptive immune response | 9.93−7 | 25 |
| Regulation of blood coagulation | 2.49−6 | 13 |