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. 2017 Oct 26;7:455. doi: 10.3389/fcimb.2017.00455

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Copyright © 2017 Li, Lu, Wang, Qin, Wang, Qiu, Wu, Huang, Zhang, Shi and Wu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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5-Fu induced mucositis and colon shortening in mice. (A) 5-Fu induced body weight changes. Data were plotted as percentage of initial body weight. (B) The occurrence of diarrhea. Data represented the evaluation scores of diarrhea. (C) The bloody stool events measured by BASO testing paper. (D) The small intestine length. (E,F) The colon length. (G) HE staining of colonic sections. (H) MPO staining of colonic sections. Values were expressed as mean ± S.E.M (n = 10/group). Data were analyzed by t-test. ^*P < 0.05, ^***P < 0.001 vs. control group.