Figure 5.

5-Fu decreased the richness and diversity of gut microbiota in feces and cecum contents of mice. (A) 5-Fu decreased the richness of gut microbiota in feces and cecum contents. Chao is an estimator of the community richness. (B,C) 5-Fu decreased the diversity of gut microbiota in feces (B, Shannon index curves and Shannon diversity histogram) and cecum contents (C, Shannon index curves and Shannon diversity histogram). (D,E) The unweighted UniFrac PCoA results of feces (D) and cecum contents (E) for beta-diversity at OTUs level. Values were expressed as mean ± S.E.M (n = 5/group, feces; n = 10/group, cecum contents). Data were analyzed by t-test. ^**P < 0.01, ^***P < 0.001 vs. control group.