Table 5.
Genes associated with cytoskeleton and intermediate filament by GO analysis found to be expressed at different levels in the skin of Super Merino (SM) and Small Tail Han (STH) sheep.
| Gene symbol | description | Log2FoldChange (SM vs STH) | FDR | GO term† |
|---|---|---|---|---|
| ACTA1 | actin, alpha 1, skeletal muscle | −2.18 | 5.30E-03 | 3 |
| CASP14 | caspase 14 | −0.92 | 4.13E-02 | 1, 5 |
| CD2AP | CD2 associated protein | −0.85 | 3.13E-02 | 3, 4 |
| CFL2 | cofilin 2 | −0.82 | 3.33E-02 | 3 |
| DES | desmin | −1.31 | 2.08E-06 | 5 |
| DMD | dystrophin | −0.71 | 2.96E-02 | 3 |
| HAP1 | huntington associated protein 1 | −1.30 | 3.95E-02 | 3 |
| IQGAP2 | IQ motif containing GTPase activating protein 2 | −0.78 | 2.25E-02 | 3, 4 |
| KRT1 | keratin 1 | −1.19 | 1.98E-02 | 1 |
| KRT10 | keratin 10 | −1.34 | 1.16E-03 | 1 |
| KRT36 | keratin 36 | 0.80 | 3.94E-02 | 2 |
| KRT79 | keratin 79 | 0.98 | 5.04E-03 | 1, 2 |
| KRTAP1-1 | keratin associated protein 1-1 | 1.01 | 3.49E-02 | 1, 2 |
| KRTAP6-1 | keratin associated protein 6-1 | 1.41 | 1.27E-02 | 2, |
| LOC101111178 | keratin, type II cytoskeletal 6A-like mRNA | −1.35 | 9.31E-04 | 1 |
| LOC101114537 | keratin-associated protein 4-9-like | 1.41 | 3.86E-02 | 1, 2 |
| LOC101115634 | keratin-associated protein 9-2 | 1.32 | 3.68E-02 | 1, 2 |
| LOC101116068 | keratin-associated protein 9-9-like | 1.30 | 3.86E-02 | NG |
| LOC105605703 | keratin-associated protein 6-2-like | 2.83 | 6.82E-04 | 2 |
| NEB | nebulin | −1.60 | 1.27E-02 | 3 |
| PDLIM3 | PDZ and LIM domain 3 | −0.83 | 4.27E-02 | 3 |
| PKN2 | protein kinase N2 | −0.88 | 2.68E-02 | 5 |
| PPP1R12A | protein phosphatase 1 regulatory subunit 12 A | −0.89 | 1.39E-02 | 3 |
| STAG2 | stromal antigen 2 | −0.99 | 4.42E-02 | 3, 5 |
| SYNE2 | spectrin repeat containing nuclear envelope protein 2 | −1.09 | 3.67E-02 | 5 |
| SYNPO2 | synaptopodin 2 | −0.90 | 6.22E-03 | 3 |
| TPM1 | tropomyosin 1 (alpha) | −0.83 | 2.51E-02 | 4 |
| ZNF175 | zinc finger protein 175 | −1.52 | 5.81E-05 | 5 |
†GO term: 1. Keratin filament (GO: 0045095); 2. Intermediate filament (GO: 0005882); 3. Actin cytoskeleton (GO: 0015629); 4. Filamentous actin (GO: 0031941); 5. Intermediate filament cytoskeleton (GO: 0045111); NG. Not given.