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. 2017 Oct 30;8:1183. doi: 10.1038/s41467-017-01239-3

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — Two-dimensional chemical structure of AMFs and AMC1β. As halide derivatives of AM1, AMFs and AMC1β share a similar AM1 structural motif with one or more halogen atoms (fluorine or chloride) added in the 4-menthylphenyl tail. The three hydrogen bond-forming groups of ABA, carbonyl, hydroxyl, and carboxyl, and their counterparts in AM1 and AMF4, are highlighted in red, blue, and green, respectively