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. 2017 Oct 25;8:287. doi: 10.3389/fendo.2017.00287

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Copyright © 2017 Ziko, Sominsky, Nguyen, Yam, De Luca, Korosi and Spencer.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Neonatal overfeeding effects on neonatal hypothalamic circuitry. (A,B) neuropeptide Y (NPY) labeling in the arcuate nucleus of the hypothalamus (ARC) and (C,D) paraventricular nucleus of the hypothalamus (PVN) of control (CL) and small litter (SL) rats at postnatal day (P) 12. (E,F) Agouti-related peptide (AgRP) labeling in the ARC and (G,H) PVN. (I,J) Proopiomelanocortin (POMC) positive cells in the ARC. (K,L) POMC labeling in the PVN. Representative photomicrographs showing NPY labeling in the (B) ARC and (D) PVN, AgRP labeling in the (F) ARC, and (H) PVN, POMC labeling in the (J) ARC and (L) PVN. Scale bars = 100 µm. Data are mean ± SEM. n = 5–6 per group.