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. 2017 Oct 19;8:1375. doi: 10.3389/fimmu.2017.01375

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Copyright © 2017 Tyrkalska, Candel, Pérez-Oliva, Valera, Alcaraz-Pérez, García-Moreno, Cayuela and Mulero.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Molecular characteristics and phylogenetic relationships of zebrafish Caiap gene. (A) Diagrams showing the domain organization of different fish, amphibians, reptiles, birds, and mammals Caiap. The CARD domains (SMART accession number SM00114) are shown as pink boxes and the ANK repeats (SMART accession number SM00248) are shown as green boxes. (B) Phylogenetic tree of vertebrate Caiap polypeptides. The tree was generated by the cluster algorithm using amino acid sequences. Numbers shown are percentages of 100 bootstrap replicates in which the same internal branch was observed. The horizontal lines are drawn proportional to the inferred phylogenetic distances, while the vertical lines have no significance.