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. 2017 Oct 23;8:754. doi: 10.3389/fphar.2017.00754

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Copyright © 2017 Sinha, Sarma, Sehgal and Medhi.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Role of stem cell in generating in vitro efficacy models for malaria. iHLC, induced human hepatocyte-like cells; hESC, human embryonic stem cells; MSP1, merozoite surface protein 1; FPH1, functional proliferation of primary hepatocytes 1; DMEs, drug metabolizing enzymes; DILI, drug-induced liver injury; CD55, clusters of differentiation; NIH 3T3, mouse embryonic fibroblast cell line; HSC, hematopoietic stem cells; HSPC, hematopoietic stem/progenitor cell; PB, peripheral blood; UCB, umbilical cord blood; BM, bone marrow.