Table 1.
Anaplastic thyroid cancer (ATC) patients and tumor characteristics in Sicily and in USA (2002–2009).
| Sicily | USA | p | |
|---|---|---|---|
| N. cases | 43 | 683 | |
| ASRw | 0.05 | 0.06 | N.S. |
| Mean age (± SD) | 71.6 (±9.7) | 70.3 (±9.7) | 0.5 |
| F (N. 25) | 73.0 (±11.4) | ||
| M (N. 18) | 69.7 (±6.2) | ||
| F/M ratio | 1.4/1.0 | 1.6/1.0 | 0.62 |
| Tumor sizea | 5.7 (±2.4) | 6.3 (±2.9) | 0.27 |
| ≤6 cm | 23/33 (69.7%) | ||
| >6 cm | 10/33 (30.3%) | ||
| Extrathyroid invasionb | |||
| Present | 27 (73%) | ||
| Absent | 10 (27%) | ||
| Coexistence with DTC | 20 (46.5%) | ||
| Staging (TNM) | |||
| IVA | 16 (37.2%) | 69 (10.1%) | <0.001 |
| IVB | 26 (60.5%) | 571 (83.6%) | |
| IVC | 1 (2.3%) | 43 (6.3%) | |
| Survival | |||
| Median (months) | 6.8 | 5.0 | 0.28 |
| Survival rate 6 months | 51.2% | 38.0% | 0.09 |
| 1 year | 37.2% | 25.0% | 0.08 |
aAvailable in 33 patients.
bAvailable in 37/43 patients.
p: USA vs Sicily.
N.S, non-significant.