Table 2.

Summary of spontaneous firing properties of mPFC- and non-mPFC-responsive cells recorded in the LS.

	Spontaneous activity: mPFC-responsive cells			Spontaneous activity: non-mPFC-responsive cells
	FR (Hz)	ISI (ms)	CV of ISI	FR (Hz)	ISI (ms)	CV of ISI
Control	4.10 ± 1.5	1635 ± 632.3	1.73 ± 0.3	12.72 ± 3.0	167 ± 33.9	1.31 ± 0.2
Vortioxetine	3.01 ± 1.3	1278 ± 328.8	1.45 ± 0.2	9.75 ± 3.1	290 ± 73.6	1.33 ± 0.1
Escitalopram	2.91 ± 1.5	2110 ± 719.3	1.12 ± 0.1	4.32 ± 0.7	350 ± 62.9	1.10 ± 0.1

No changes in firing rate, ISI and CV of ISI were observed in the LS with vortioxetine and escitalopram treatment. Data are presented as Mean ± SEM and analyzed using one-way ANOVA with Tukey post hoc analysis (mPFC-responsive: n = 14 cells for control, n = 13 cells for vortioxetine-treated, and n = 11 cells for escitalopram-treated groups; non-mPFC-responsive: n = 19 cells for control, n = 15 cells for vortioxetine-treated, and n = 15 cells for escitalopram-treated groups).