Table 3.

Summary of spontaneous firing properties of mPFC- and non-mPFC-responsive cells recorded in the medial shell of the nucleus accumbens (msNAc).

	Spontaneous activity: mPFC-responsive cells			Spontaneous activity: non-mPFC-responsive cells
	FR (Hz)	ISI (ms)	CV of ISI	FR (Hz)	ISI (ms)	CV of ISI
Control	4.26 ± 1.7	1452 ± 714.9	1.42 ± 0.2	13.77 ± 3.2	168 ± 36.9	1.15 ± 0.2
Vortioxetine	2.93 ± 0.8	2235 ± 859.6	1.21 ± 0.2	10.83 ± 2.6	217 ± 96.9	1.29 ± 0.2
Escitalopram	3.03 ± 1.4	1852 ± 624.4	1.54 ± 0.3	12.48 ± 2.2	143 ± 30.1	0.90 ± 0.1

No changes in firing rate, ISI or CV of ISI were observed with vortioxetine and escitalopram treatment. Data are presented as Mean ± SEM and analyzed using one-way ANOVA with Tukey post hoc analysis (mPFC-responsive: n = 11 cells for control, n = 13 cells for vortioxetine-treated, and n = 12 cells for escitalopram-treated groups ; non-mPFC-responsive: n = 18 cells for control, n = 13 cells for vortioxetine-treated, and n = 19 cells for escitalopram-treated groups).