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. Author manuscript; available in PMC: 2017 Oct 31.

Published in final edited form as: Chem Rev. 2017 May 12;117(12):7857–7877. doi: 10.1021/acs.chemrev.7b00046

Pol α-primase encountering a UV-induced lesion ( ) on a lagging strand template. This model shown in cartoon form only displays pol α-primase on the lagging strand template for simplicity.

Inline graphic — Pol α-primase encountering a UV-induced lesion ( ) on a lagging strand template. This model shown in cartoon form only displays pol α-primase on the lagging strand template for simplicity.