Table 1.
Summary of key epidemiological features of ST313 sampled by PHE. Full metadata for all isolates in this study is available in Additional file 2: Table S2
| A. Association between isolation source and travel to sSA. Total = 48a | ||
| Extra-intestinal infection | Gastro-intestinal infection | |
| Reported travel to sSA | 6 | 2 |
| No reported travel to sSA | 2 | 38 |
| OR = 57.0 (95% CI = 6.7–484.8), p value = 0.0002 | ||
| B. Association between lineage 2 infection and travel to sSA. Total = 51b | ||
| Lineage 2 | Non-lineage 2 | |
| Reported travel to sSA | 7 | 1 |
| No reported travel to sSA | 2 | 41 |
| OR = 143.5 (95% CI = 11.4–1802.9), p value = 0.0001 | ||
| C. Association between lineage 2 infection and extra-intestinal infection. Total = 72c | ||
| Lineage 2 | Non-lineage 2 | |
| Extra-intestinal infection | 10 | 3 |
| Gastro-intestinal infection | 1 | 57 |
| OR = 190.0 (95% CI = 17.9–2014.0), p value < 0.0001 | ||
a51 individual patient isolates with travel information, but three with source unknown
b51 individual patient isolates with travel information
c75 individual human patient isolates in total, but three with source unknown. One isolate not included in phylogeny due to poor quality sequence, so lineage unknown